Rheumatoid factor (RF) is a protein that is produced by the immune system which attacks healthy tissue. Presence of RF in the blood can indicate an autoimmune disease. RF indicates for Rheumatoid arthritis & also in cases of chronic infection and other systemic inflammatory conditions. Individuals, more than 65 years of age may also show positive RF results. In such cases common IgM RF, & both IgA RF and IgG RF have been detected. IgA RF has been related to the more severe form of the disease.
To check for autoimmune diseases
High level of rheumatoid factor indicates a tendency towards more severe rheumatoid disease.